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Laurus Labs, Unitaid and the Clinton Health Access Initiative, announce agreement to accelerate development of best-in-class second- and third-line HIV medication for children

Posted On: 2021-09-14 08:07:56 (Time Zone: UTC)


Laurus Labs Limited ( BSE: 540222, NSE: LAURUSLABS, ISIN: INE947Q01028), a leading research & development-driven and fully integrated pharmaceutical and biotech company in India ("the Company"), announces that the development is underway based on an agreement launched in June 2021 the Company, Unitaid and the Clinton Health Access Initiative (CHAI), to accelerate the development, commercialization, and registration of the bestin-class second- and third-line HIV treatment darunavir boosted with ritonavir (DRV/r) for children. Despite being available in high-income countries for over a 15-year period, a generic, fixed-dose combination pediatric version of DRV/r is still not available. Through this agreement, Unitaid and CHAI are working with the Company to finally address this critical need and ensure CLHIV (Children Living with HIV/AIDS) have access to high-quality second- and third-line HIV treatment.

Unitaid Executive Director Dr. Philippe Duneton said, "Enabling children and young people to have access to the best possible HIV treatment is a key priority for Unitaid - whether that's first, second, or third-line treatment. This agreement is a welcome step towards having a long-awaited pediatric formulation of DRV/r available, as we strive to achieve the global goal of 90% of people living with HIV receiving antiretroviral therapy."

Second and third-line therapies are critical for CLHIV where the World Health Organization (WHO)-recommended first-line treatment dolutegravir (DTG) may not be an option due to medication resistance or intolerance. Currently available secondand third-line treatments are often difficult for children to take due to bitter taste and difficult forms of administration.

"A pediatric version of DRV/r has been a global health priority since 2013, but is still not available, leaving thousands of children without the lifesaving medication they need," said Ann Veneman, interim Co-CEO of CHAI. "The innovative incentive program announced today will enable development of an effective pediatric medication that will save the lives of children living with HIV."

The product development collaboration between Unitaid, CHAI, and Laurus Labs was spearheaded through Unitaid's investment in CHAI since 2016 to bring the best HIV medications to market more quickly and integrate them into treatment programs in low- and middle-income countries that need them the most.

Understanding the small market size for a pediatric version of DRV/r, the initiative has provided Laurus with a financial incentive for a portion of their development and commercialization costs. CHAI will work closely with Laurus Labs to provide technical and regulatory support to enable accelerated generic development and regulatory submission of the medication. Commenting on the collaboration in development of the new second line and third line pediatric treatment, Dr. Satyanarayana Chava, Founder & CEO, Laurus Labs, said, "we are excited about this innovative mechanism to accelerate the availability of pDRV/r regimen for children living with HIV.

The collaboration between Laurus Labs, CHAI, and Unitaid can positively impact over 100,000 CLHIVs and help them in leading a better life especially in their formative years."

Shares of Laurus Labs Limited was last trading in BSE at Rs. 645.9 as compared to the previous close of Rs. 656. The total number of shares traded during the day was 67056 in over 2693 trades.

The stock hit an intraday high of Rs. 654.8 and intraday low of 644.9. The net turnover during the day was Rs. 43551926.


Source: Equity Bulls

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