Mutual Funds Commodities Research Tax Planning IPO Our Team Contact Us    
Google
Web www.equitybulls.com
Stock Report

| More

Suven Life Sciences presented exploratory sub-group analyses data from Masupirdine (SUVN-502) Phase 2A Study at the Advances in Alzheimer's and Parkinson's Therapies (AAT-AD/PD) focus meeting 2020

Posted On: 2020-04-06 17:37:14


Suven Life Sciences presented exploratory sub-group analyses data from Masupirdine (SUVN-502) Phase 2A proof of concept Study in Patients with Moderate Alzheimer's Disease (AD) at the Advances in Alzheimer's and Parkinson's Therapies (AAT-AD/PD™) focus meeting 2020. This meeting, originally scheduled to take place in Vienna, Austria, was converted to a virtual meeting due to the COVID-19 pandemic.

The outcome of the analyses was discussed through a virtual symposium chaired by Dr. Jeffrey Cummings, MD, ScD., USA; Dr. Alireza Atri, MD, PhD, USA highlighted the potential signals of benefit for masupirdine on cognition, function, and global progression in Alzheimer's disease; Professor Clive Ballard, MD, M.R.C. Psych. UK discussed the potential benefits of masupirdine on neuropsychiatric symptoms in patients with Alzheimer's disease. The symposium panel concluded that if the exploratory analyses hold in the confirmatory trial, masupirdine could be a first line treatment option for the management of agitation/aggression in patients with Alzheimer's disease. In addition, the panel also opined that masupirdine may have potential benefit on cognition, function, and global progression in Alzheimer's disease.

Key findings from exploratory analyses:

- In participants whose memantine plasma concentrations were =100 ng/mL at Week 26, there was lesser cognitive decline (ADAS-Cog 11) in participants taking masupirdine than in those on placebo (p<0.05) at Week 26. There were congruent signals for beneficial effects on MMSE, ADCS-ADL, NPI and CDR-SB as well.

- Masupirdine significantly reduced agitation/aggression in patients having baseline symptoms (p<0.001; Cohen's d = 0.45 at Week 13).

- Masupirdine also attenuated delusions and/or hallucinations in patients with dementia of the Alzheimer's type (p=0.016; Cohen's d = 0.58 at Week 13).

- In patients with psychotic symptoms, masupirdine treatment had beneficial effects on cognition (p=0.067; Cohen's d = 0.57 at Week 26).

- Masupirdine showed sustained and durable efficacy on neuropsychiatric symptoms for the entire study duration of 26 weeks.

- Masupirdine is safe and well tolerated without significant adverse events.

These exploratory and thought-provoking observations merit better understanding and further possible investigations of masupirdine effects and its role as a potential future drug in the AD pharmaceutical armamentarium.

This sub-group analysis demonstrates potential utility of Masupirdine in cognition and neuropsychiatric symptoms in patients with Alzheimer's disease as follows:

1. Potential benefit on cognition, function, and global progression in Alzheimer's disease.

2. Potential beneficial effects on several domains of neuropsychiatric inventory related to agitation/aggression and delusions/hallucinations.

3. Potential beneficial effects on cognition in patients with psychotic symptoms.

Shares of SUVEN LIFE SCIENCES LTD. was last trading in BSE at Rs.21.35 as compared to the previous close of Rs. 20.35. The total number of shares traded during the day was 241340 in over 963 trades.

The stock hit an intraday high of Rs. 21.35 and intraday low of 19.35. The net turnover during the day was Rs. 5094866.


Source: Equity Bulls

Click here to send ur comments or to feedback@equitybulls.com





Other Headlines:

ITC Ltd forms subsidiary ITC IndiVision Limited

Celent Recognizes Majesco with XCelent Award for Depth of Service in the North American Policy Administration Systems 2020 Personal, Commercial and Specialty ABCD Vendor View Report

Sadbhav Engineering Ltd reports Rs. 886.63 crore PAT in Q4 FY20

NLC India Ltd's project in Andaman commissioned

Swarnsarita Gems Ltd Q4 consolidated PAT at Rs. 0.26 crore

PNB Housing Finance Ltd reworks business plan for FY2020-21

Arihant Capital Markets Ltd posts Rs. 2.18 crore consolidated PAT in Q4 FY20

Inducto Steel Ltd Q4 FY20 net profit at Rs. 0.52 crore

Dai-Ichi Karkaria Limited enters into agreement for sale of land

Sun Pharma launches 'Thank you Doctor' campaign

Reliance and bp launch 'Jio-bp' partnership

Arihant Capital Markets Ltd Board approves Dividend for FY20

HPL Electric & Power Ltd Q4 FY20 consolidated PAT drops to Rs. 2.51 crore

HPL Electric & Power Limited board recommends final dividend of Rs. 0.15

TCS board declares interim dividend of Rs. 5 for FY2020-21

TCS Q1FY21 consolidated PAT lower at Rs. 7008 crore

Kabra Extrusiontechnik Ltd posts consolidated PAT of Rs. 0.74 crore in Q4

HCC FY20 Revenue at Rs. 3,676 Crore; EBITDA margin at 12.7%

Jaguar Land Rover Reports Q1 Fiscal 2020/21 Retail Sales

Muthoot Capital Services Limited completed transaction of Rs. 100.89 crores through securitization of portfolio

Vessel Seamec Gallant's contract extended for 1 year

W H Brady & Co. Ltd. Q4 FY20 consolidated loss at Rs. 0.24 crore

Arvind Fashions Ltd reports loss of Rs. 204.33 crore in Q4 FY2020

Vedanta readies for post-Covid economic recovery, strengthens its Advisory Board by appointing former Secretary, GoI and ex-SAIL Chief

Arvind Fashions Ltd signs agreement for sale of Flying Machine business

Ind-Ra affirms rating of Arvind SmartSpaces Limited

ALANKIT Ltd enters into Business Correspondent Agreement with IDBI Bank

Hexaware Launches COCO-Unified Teams Bot for Improved Employee Experiences & Seamless Return to Workplaces

Zensar featured in ISG's 2020 Digital Case Studies Book

Britannia Industries Ltd board to approve Q1 results on July 17, 2020

Flipkart Group and Arvind Fashions Strengthen Partnership

SBI Life Insurance Company Ltd board to consider Q1 results on July 21, 2020

BHEL successfully commissions World's first Solar PV Plant for Rail Traction application

Praj strides into the next frontier of Bioeconomy

Hitachi ABB Power Grids India wins INR 120 crore order for Indian Railways electrification

Karur Vysya Bank partners with Tata Motors to offer car loans at attractive terms

IIFL Finance Ltd allots 2000 NCDs

YES Bank files RHP for FPO

Linc Pen and Plastics Ltd update on FY21

Strides receives USFDA approval for Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate Capsules

ICICI Prudential Life Insurance Company Ltd board to approve 1st quarter FY21 results on July 21, 2020

Sharika Enterprises Ltd bags order from BHEL

Swelect Energy Systems Limited board recommends final dividend of Rs. 0.75

SpiceJet facilitates insurance of passengers for COVID-19 hospitalisation starting at Rs. 443/-

Shoppers Stop Limited opens new store at Phoenix Palassio - Lucknow

PI Industries Ltd closes QIP, fixes price as Rs. 1470

YES Bank has sold 2.66% stake in CG Power & Industrial Solutions Limited

NMDC's excellent performance at Bailadila Projects, Chhattisgarh, during lockdown

The Phoenix Mills Ltd. opens doors of its grand palatial shopping mall, Phoenix Palassio, in Lucknow

Swelect Energy Systems Ltd Q4 consolidated loss at Rs. 14.87 crore







Website Created & Maintained by : Chennai Scripts
West Mambalam, Chennai - 600 033,
Tamil Nadu, India

disclaimer copyright © 2005 - 2019