Pharma major Lupin Limited {Lupin) announced the launch of Imatinib Mesylate Tablets, 100 mg {base) and 400 mg {base). Lupin's alliance partner Natco had received an approval from the United States Food and Drug Administration (U.S. FDA) earlier.
Lupin's Imatinib Mesylate Tablets, 100 mg (base) and 400 mg (base), is the generic version of Novartis Pharmaceuticals Corporation's (Novartis) Gleevec® Tablets, 100 mg and 400 mg. It is indicated for the treatment of:
- Newly diagnosed adult and pediatric patients with Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML) in chronic phase.
- Patients with Philadelphia chromosome positive chronic myeloid leu kemi a (Ph+ CML) in blast crisis (BC), accelerated phase (AP), or in chronic phase (CP) after failure of interferon-alpha therapy.
- Adult patients with relapsed or refractory Philadelphia chromosome positive acute lymphoblastic leukemia {Ph+ ALL).
- Adult patients with myelodysplastic/myeloproliferative diseases {MDS/MPD) associated wit h PDGFR (plateletderived growth factor receptor) gene re-arrangements as determined with an FDA-approved test.
- Adult patients with aggressive systemic mastocytosis (ASM) without the D816V c-Kit mutation as determined with an FDA-approved test or with c-Kit mutational status unknown.
- Adult patients with hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukemia {CEL) who have the FIP1L1-PDGFRa fusion kinase {mutational analysis or FISH demonstration of CHIC2 allele deletion) and for patients with HES and/or CEL who are FIP1L1-PDGFRa fusion kinase negative or unknown.
- Adult patients with unresectable, recurrent and/or metastatic dermatofibrosarcoma protuberans (DFSP). Imatinib Mesylate Tablets, 100 mg {base) and 400 mg (base), had annual sales of approximately USD 548 million in the US (IQVIA MAT May 2019).
Shares of LUPIN LTD. was last trading in BSE at Rs.751.5 as compared to the previous close of Rs. 733.75. The total number of shares traded during the day was 51046 in over 1395 trades.
The stock hit an intraday high of Rs. 753.5 and intraday low of 730.85. The net turnover during the day was Rs. 38072272. |
